Step 1:
Hold the patch directly over knot(s) for 3-4 minutes.
Step 2:
Repeat Step 1 as necessary for as many knots as you have.
Step 3:
If you feel the discomfort / tension returning, immediately put the patch back on the source and you should feel relief within 1-2 minutes.
Step 4:
Leave the patch over your most tense knot overnight. Repeat as many nights as necessary, for as many knots as necessary.